Description
Tetrastark 5.5% Injection – Broad-Spectrum Veterinary Antibiotic
Tetrastark 5.5% Injection is a broad-spectrum bacteriostatic antibiotic formulated for veterinary use. It provides antimicrobial activity against a wide range of susceptible Gram-positive and Gram-negative bacteria, as well as Mycoplasma, some protozoa, Rickettsia, Chlamydia, Spirochetes, and other susceptible microorganisms.
Its broad spectrum makes Tetrastark 5.5% a versatile option for veterinary disease management where infections caused by susceptible organisms are confirmed or strongly suspected.
Broad-Spectrum Antibacterial Activity
Tetrastark 5.5% has activity against numerous Gram-positive organisms, including susceptible Corynebacterium, Clostridia, Erysipelothrix, Actinomycetes, Staphylococcus, and Streptococcus species.
It also acts against a range of Gram-negative microorganisms, including susceptible Escherichia coli, Salmonella, Pasteurella, Haemophilus, Brucella, Pseudomonas, Bordetella, Chlamydia, and Rickettsia species.
The supplied product information also indicates activity against Mycoplasma, some protozoal organisms such as Anaplasma and Leptospira, Spirochetes, and certain large viruses.
Systemic Absorption and Distribution
Following administration, Tetrastark 5.5% is absorbed from the injection site and distributed throughout the body. According to the supplied product information, the active substance penetrates various organs, tissues, and body fluids, including crossing the placental barrier.
This systemic distribution allows the antibiotic to reach susceptible microorganisms located in different areas of the body.
Excretion and Veterinary Considerations
The supplied information states that the active substance is excreted through urine, bile, faeces, and milk. This is particularly important when treating food-producing animals.
Veterinarians and farmers should therefore observe the manufacturer’s recommended dosage, treatment duration, withdrawal periods, and species-specific precautions. Antibiotics should be used responsibly and preferably following veterinary diagnosis or professional guidance.
Key Benefits
- Broad-spectrum bacteriostatic antibiotic
- Active against susceptible Gram-positive bacteria
- Effective against susceptible Gram-negative bacteria
- Activity against Mycoplasma and selected other microorganisms
- Systemically absorbed after injection
- Distributed throughout body tissues and fluids
- Suitable for veterinary infectious disease management
- Useful where susceptible bacterial infections are confirmed
Tetrastark 5.5% Injection should always be administered according to the manufacturer’s instructions and under appropriate veterinary guidance.
Indications:
TETRASTARK 5.5% is a bacteriostatic antibiotic with a wide spectrum of activity against Gram-positive (Cocci spp., Corynebacterium spp., Clostridia spp., Erysipelothrix spp., Actinomycetes spp., Staphylococcus spp., Streptococcus spp., etc.) and Gram-negative (Escherichia coli, Salmonella spp., Pasteurella spp., Haemophilus spp., Brucella spp., Pseudomonas spp., Bordetella spp., Chlamydiae spp., Rickettsiae spp., etc.) microorganisms, Mycoplasmas spp., some protozoa (Anaplasma spp., Leptospira spp., Spirochetes spp., etc.) and large viruses. It is absorbed from the injection site and penetrates into all the body organs, tissues and fluids, the placenta barrier included. It is excreted in an active form in urine, bile, faeces, and milk.
TETRASTARK 5.5% is recommended in infections of the respiratory and urogenital tracts, gastrointestinal canal, and the soft tissues; in septic conditions; in secondary bacterial infections, in viral diseases caused by oxytetracycline-sensitive pathogenic microorganisms (as mentioned above); in mastitis-metritis-agalactia (MMA) syndrome in sows; in metritis, mastitis, post-operative conditions, enterotoxemia, pyelonephritis, tetanus, foot rot, malignant edema, infectious polyarthritis, spirocheyosis, anaplasmosis etc. in large ruminants such as calves, cattle, camels etc. and small ruminants such as goats, sheep etc, horses, pigs, dogs, cats and birds.
Dosage & Administration
| Species | Dosage |
| Large ruminants & horses | 1.5 – 2.5 ml / 50kg live body weight
2.5 ml /50kg live body weight in cases of Anaplasmosis |
| Sheep and goats | 1 – 1.5 ml / 50kg live body weight |
| Pigs | 0.25 – 0.5 ml / 10kg live body weight |
| Dogs | 0.5 ml / 10kg live body weight |
| Cats | 0.05 ml / kg live body weight |
| Fowls | 0.15 – 0.25 ml / kg live body weight |
NB:
- The higher doses of each dosage scale are intended for the younger animals of the respective species.
- For intramuscularly (IM), subcutaneously (SC), and slowly intravenously administration.
- The dose on a single site in intramuscular administration must not exceed 10ml for large ruminants, 4.5ml for pigs, 3-4.5 ml for sheep and goats and 1 ml for small animals.
- Before use, warm up the solution to body temperature.
- TETRASTARK 5.5% must be applied once daily for 3 – 5 consecutive days.
Contra-indications:
Animals with kidney impairment; pregnant animals; newborn animals. Discoloration of teeth in young animals (it may lead to brown coloration of teeth). After intramuscular administration, local reaction can occur, which disappear in a few days. Do not administer intravenously to horses, dogs and cats.
Withdrawal periods:
Meat: 10 days
Milk: 4 days
Responsible Antibiotic Use
Not every infection requires an antibiotic, and antimicrobial treatment should be based on appropriate diagnosis whenever possible. Correct use helps improve treatment outcomes and supports responsible antimicrobial stewardship.
Storage:
Store below 30°C in a cool, dry place protected from light and heat.

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