ISONOR | ISOMETAMIDIUM INJECTION

Description

Isonor Isometamidium – Veterinary Treatment for Trypanosomiasis

Isonor, containing Isometamidium, is a veterinary trypanocidal medicine used for the curative and preventive treatment of animal trypanosomiasis. Isometamidium belongs to the aminophenanthridinium group of compounds and is widely used in veterinary parasite-control programmes where susceptible Trypanosoma infections are a concern.

Trypanosomiasis is an important parasitic disease affecting livestock and other animals. It can cause fever, weakness, anaemia, weight loss, poor appetite, reduced productivity, and general deterioration in affected animals. In serious cases, untreated infection can lead to significant production losses and death.

Broad Activity Against Trypanosoma Species

Isonor Isometamidium has a spectrum of activity covering important Trypanosoma species, including:

• Trypanosoma vivax
• Trypanosoma congolense
• Trypanosoma brucei
• Trypanosoma evansi

These parasites can affect different animal species and may cause significant disease, particularly in regions where trypanosomiasis is prevalent.

Curative and Preventive Treatment

One of the important applications of Isonor is its use in both curative and preventive trypanosomiasis management. Curative treatment is intended for animals affected by susceptible trypanosome infections, while preventive use may form part of a strategic disease-control programme in areas where animals face an ongoing risk of exposure.

Preventive treatment should be based on veterinary advice and local disease conditions to ensure responsible and effective use.

Target Animal Species

According to the supplied product information, Isonor Isometamidium can be administered to several animal species, including:

Ruminants:
Cattle, buffalo, goats, and sheep.

Equines:
Horses and donkeys.

Other species:
Camels and dogs.

Key Benefits

• Contains Isometamidium
• Provides trypanocidal activity
• Used for curative treatment of trypanosomiasis
• Can be used for preventive trypanosomiasis control
• Active against several important Trypanosoma species
• Suitable for multiple livestock and animal species
• Supports strategic parasite management
• Helps protect animal health and productivity

Responsible Use

Accurate diagnosis is important because several diseases can produce similar signs, including fever, anaemia, weakness, and weight loss. Isonor Isometamidium should be administered according to the manufacturer’s instructions and veterinary recommendations.

Farmers should follow the correct dosage, administration method, precautions, treatment schedule, and applicable withdrawal periods for food-producing animals.

Properties:

Isometamidium, an aminophenathridium compound, has trypanocidal action used in curative and preventive treatment of animal trypanosomiasis.
Its spectrum of activity ranges from T. vivax, T. congolense to T. brucei and T. evansi. It could be administered to the following target species: ruminants (cattle, buffalo, goat, sheep), equines (horses, donkeys), camels and dogs.
As the mechanism of action of ISONOR (isometamidium) and DIMINOR (diminazene) acts on different targets, they could be combined in integrated programmes in order to control the development of resistant strains and potentialize preventive action of isometamidium. Duration of the preventive effect varies from 8 to 16 weeks according to the fly challenge.
Indications: cattle (incl.zebu), buffaloes, sheep, goats, camels, equines, dogs: Curative and preventive treatment of trypanosomiasis.

Administration and Dosage:

Cattle, buffaloes, sheep, goats:

Deep intramuscular route in the neck muscles.
– Sterile or distilled water should be used to prepare the solution, which must be used extemporaneously or stored in the fridge for 24 hours maximum.
– The dosage should be adjusted according to the sensitivity of local strains of trypanosoma.

Withdrawal period:

Meat: 1 month.
Milk: nil.

Why Choose Isonor Isometamidium?

For farms operating in areas where trypanosomiasis presents a significant threat, Isonor Isometamidium provides a targeted veterinary option for managing susceptible Trypanosoma infections. Used as part of a broader animal health programme, it can help protect livestock and other susceptible animals from the effects of trypanosomiasis.