Description
Description
The combination of amoxycillin and colistin acts additive. Amoxycillin is a semisynthetic broadspectrum penicillin with a bactericidal action against both Gram-positive and Gram-negative bacteria. The spectrum of amoxycillin includes Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase-negative Staphylococcus and Streptococcus, spp. The bactericidal action is due to inhibition of cell wall synthesis.
Amoxicillin is mainly excreted in urine. A major part can also be excreted in bile. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.
Amoxicillin is mainly excreted in urine. A major part can also be excreted in bile. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.
Indications
Gastrointestinal, respiratory, and urinary tract infections caused by amoxicillin and colistin-sensitive micro-organisms like Campylobacter Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus spp. in calves, goats, poultry, sheep and swine.
Dosage:
For oral administration.
– Calves, goats, and sheep:
Twice daily 5 grams per 100 kg body weight for 3-5 days.
– Poultry and Swine:
1 kg per 1000 – 2000 litre drinking water for 3 – 5 days.
Note: for pre-ruminant calves, lambs, and kids only.
Withdrawal times:
– For meat: 8 days.
Storage:
Dark and dry below 30 °C. Do not freeze.
Note: Keep away from children.
