ZYPRONOR 100ml

INDICATIONS

ZYPRONOR belongs to the fluoroquinolone group. Its bactericidal action has a broad spectrum activity, high safety, and bactericidal activities against Mycoplasma, gram positive and gram-negative pathogen.

DOSAGE AND ADMINISTRATION

By oral administration,

• Poultry: 1ml per 2 – 4L of drinking water (50-100ppm) for 3-5 days.
• Young ruminant and Rabbit: 1ml per 50kg body weight for 3-5 days.

CONTRAINDICATION

Avoid use in young animals because of the risk of cartilage injury. Use cautiously in animals that may be prone to seizures, such as epileptics. It is not recommended to administer ciprofloxacin to horses.

DRUG INTERACTIONS

Fluoroquinolones may increase concentrations of theophylline if used concurrently. Coadministration with divalent and trivalent cations, such as products containing aluminum (e.g., sucralfate), iron, and calcium, may decrease absorption. Do not mix in solutions or in vials with aluminum, calcium, iron, or zinc because chelation may occur.

PHARMACOLOGICAL ACTIONS

Fluoroquinolone antibacterial. Acts to inhibit DNA gyrase and cell DNA and RNA synthesis, Bactericidal. Broad antimicrobial activity. Ciprofloxacin is active against gram-negative bacilli, including Enterobacteriaceae, and some gram-positive cocci, including Staphylococcus. Ciprofloxacin is more active against Pseudomonas aeruginosa than other fluoroquinolones, but resistance is possible.

Multi-resistant bacteria, including gram-negative bacilli of the Enterobacteriaceae, and methicillin-resistant strains of Staphylococcus, are likely to be resistant to ciprofloxacin and other fluoroquinolones.

WITHDRAWAL PERIOD

• Poultry: Chicken: 5 days.
• Eggs: 5 days.

Young ruminant and Rabbit: Meat: 5 days.

Do not use in animals producing milk for human consumption.

STORAGE

Store below 30°C, keep in a dry place and preserve in tight

containers.

SHELF LIFE

4 years