TOLTRANOR 2.5% 100ml

INDICATION

FOR THE TREATMENT OF COCCIDIOSIS IN CHICKEN, CALVES, AND PIGLETS.

Toltranor is effective against Eimeria acervulina, E. brunetti, E. maxima, E. necatrix, E. tenella, E. Mitis. Toltrazuril has been used as a treatment for equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona.

DOSAGE AND ADMINISTRATION

For oral administration.

• Poultry: 1ml per 1 liter of drinking water (25ppm) for 2 consecutive days.

OR 3mls per liter of drinking water (75ppm) for 8hrs per day for 2days

• Calves: 15mg/kg body weight.
• Piglets: 20mg/kg body weight.

CONTRAINDICATION

Do not use in animals with known hypersensitivity to the active substance.

WARNING

Toltrazuril does not interfere with the development of immunity against coccidiosis.

As with all anticoccidials, prolonged use may result in the development of resistant strains.

PHARMACOLOGICAL ACTIONS

Toltrazuril is an anticoccidial of the triazinetrione group, active against Eimeria spp. Toltrazuril induces changes in the fine structure of the developmental stages of coccidia. These are caused primarily by swelling of the endoplasmic reticulum and of the Golgi apparatus, abnormal changes to the perinuclear space, and disturbances in cell division. Toltrazuril causes a decrease in the activity of respiratory chain enzymes in the parasites.

WITHDRAWAL PERIOD

• Poultry: Chicken: 14 days.

Eggs: Do not use in birds producing eggs for human consumption.

• Calves, Piglets: Meat: 14 days.

STORAGE: Keep in well-closed containers, stored in a dry and cool place below 30 °C, protect from light.