PHILODIC DICLOFENAC SODIUM INJ.

Philodic Diclofenac Sodium is a clear, colorless liquid free from visible particles.

INDICATIONS:

PHILODIC diclofenac sodium injection is suitable as initial therapy for inflammatory and degenerative rheumatic diseases as well as for the treatment of painful conditions due to inflammation of non-rheumatic origin.

WARNINGS:

Administer with caution to patients with hepatic or renal failure. Serious interactions have been reported after the concomitant use of methotrexate and diclofenac.

DOSAGE AND DIRECTIONS FOR USE:

Not intended for intravenous route administration. For adults, the dosage is generally one PHILODIC-diclofenac sodium injection daily, injected deep intragluteally into the upper outer quadrant. By way of exception, in severe cases, two injections, separated by an interval of a few hours, can be given per day(one into each buttock).

PHILODIC-diclofenac sodium injection should not be given for more than a few days.

SIDE EFFECTS AND SPECIAL PRECAUTIONS:

Patients may complain of nausea and diarrhea, headache, tinnitus, or dizziness. Peripheral oedema and skin reactions, such as drug rash and eczema, have also been encountered. Central nervous system side-effects, such as tiredness, insomnia, nervousness, depression, or irritability, have occurred. Blurred vision and other ocular reactions. Sensitivity reactions, (e.g. bronchospasm, anaphylactic/ anaphylactoid systemic reactions), elevated transaminase levels, jaundice, hepatitis, renal failure, and nephritic syndrome, may occur. Dyshematopoiesis (leucopenia, thrombocytopenia, aplastic anemia) and erythema multiform have been observed. Agranulocytosis and hemolytic anemia have been observed. Abscesses and local necrosis have also occurred, particularly in elderly diabetics.

STORAGE INSTRUCTIONS:

Store in a dry place below 30°C,

protected from heat and light.

Keep all medicines out of the reach of children.