GENTADOXTOM | GENTAMYCIN | DOXYCYCLINE

Indications

GENTADOXTOM is indicated for the treatment of infections caused by micro-organisms susceptible to gentamycin and/or doxycycline.

GENTADOXTOM is indicated for the treatment of gastrointestinal infections and respiratory tract infections in calves, lamb, pigs, and poultry. GENTADOXTOM is a potent antibacterial product and useful in most infective diseases in the targeted animals.

Description

GENTADOXTOM is a combination containing gentamicin and doxycycline.

Gentamycin belongs to the group of amino-glycoside antibiotics and has bactericidal action mainly against Gram-negative bacteria E. coli, Klebsiella, Pasteurella, and Salmonella spp.

Doxycycline is a tetracycline antibiotic and acts bacteriostatic against a large number of Gram-positive and Gram-negative bacteria such as Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp.

Doxycycline is also active against Chlamydia, Mycoplasma, and Rickettsia spp. It also acts against Mycoplasma spp, Rickettsiae, and Chlamydia spp.

The action of doxycycline is based on the inhibition of bacterial protein synthesis.

Gentamycin is not absorbed from the gastrointestinal tract and therefore acts locally.

Doxycycline has a great affinity to lung tissues; therefore, it is recommended especially for respiratory tract infections.

This combination provides an intensive antibacterial effect in the gastrointestinal tract and a rapid and intensive systemic effect after absorption.

PROPERTY: It is light yellow powder.

Contra-Indications

• Do not administer to animals hypersensitive to amino-glycosides and/or tetracyclines.
• Do not use in animals with an impaired kidney function or an impaired liver function.
• Do not use in animals with an active microbial digestion.
• Not for use in animals from which milk or eggs are produced for human consumption.

Side Effects

Hypersensitivity reactions like gastrointestinal disturbances or changes of intestinal flora.

Prolonged application of high doses may result in neurotoxicity, ototoxicity, or nephrotoxicity.

Incompatibility with Other Drugs

Do not administer concurrently with penicillin, cephalosporins, quinolones, and cycloserine.

Dosage and Administration

For oral administration via feed or drinking water.

Poultry: 100g per 400 liters of drinking water for 3 – 5 days.

Calves, lambs, and kids: 1 g per 50 kg bodyweight twice daily for 4 – 6 days.

Pigs: 100 g per 200 liters of drinking water for 4 – 6 days.

Mixed with feed, use the product immediately.

Mixed with drinking water, use the product within 24 hours.

Withdrawal Period

Meat

Calves, lambs, and kids: 14 days.

Pigs: 8 days.

Poultry: 7 days.

Not for use in animals from which milk or eggs are produced for human consumption.

Storage

Store in a dry and dark place between 8 °C and 25 °C. Store in closed packing.

Packing

100g/Bag, 100Bags/Carton or accordingly.