COLISTIN SULPHATE | 5.0

Colistin Oral Solution / Premix

Description:

Colistin is a polymyxin-class antibiotic known for its potent bactericidal activity against Gram-negative bacteria. Unlike broad-spectrum antimicrobials, Colistin is a narrow-spectrum antibiotic, which allows it to effectively target and eliminate specific pathogenic bacteria without disturbing the beneficial gut flora excessively.

Mode of Action:

Colistin acts by disrupting the bacterial cell membrane integrity, causing leakage of cellular contents and bacterial death. It is highly effective against Gram-negative pathogens, including Escherichia coli, Salmonella spp., and Pseudomonas aeruginosa, which are commonly implicated in gastrointestinal infections in farm animals.

Indications:

Colistin is indicated for the treatment and control of gastrointestinal infections in calves, pigs, and poultry caused by colistin-sensitive organisms. It is particularly useful in managing bacterial enteritis, colibacillosis, and salmonellosis.

Target Species:

• Calves

• Swine (pigs)

• Poultry (broilers and layers)

Advantages:

• Rapid onset of action against targeted bacteria

• Reduced risk of resistance when used responsibly

• Minimal systemic absorption; acts locally in the gut

• Helps improve growth performance by reducing bacterial load in production animals

Administration:

Administer orally via drinking water or feed as directed by a licensed veterinarian. Dosage should be based on the severity of the infection and the animal species.

Contra-indications:

Administration to animals with a seriously impaired renal function.

ADVERSE REACTION:

No adverse reactions have been seen according to the prescribed usage and dosage.

Dosage and Administration:

Orally via drinking water or feed.

Poultry: 1g per 10-12 litres of drinking water during 3-5 days.

Calves: 2.5g per 200 kg bodyweight, twice daily, during 5-10 days.

Sows: 1g per kg feed during 3-5 days.

Piglets: 1g per 2.5 kg feed during 3-5 days.

Mixed with feed, the product should be used immediately.

Medicated drinking water should be used within 24 hours.

Precautions:

Withdrawal periods must be observed for animals intended for human consumption. Do not use in animals with known hypersensitivity to polymyxins.

Withdrawal time:

For meat: 2 days.

For eggs: 1 day.

STORAGE:

Store in a dry, dark place.

Store in closed packing.

Keep medicine away from children.