CEFQUINOR 100ml

Indications for use:

For the treatment of bacterial infections in cattle and pigs caused by the Gram-positive and Gram-negative microorganisms sensitive to cefquinome.

Cattle: Respiratory disease caused by Pasteurella multocida and Mannheimia haemolytica Digital dermatitis, infectious bulbar necrosis, and acute interdigital necrobacillosis (foul in the foot) Acute E.coli mastitis with signs of systemic involvement.

Calves: E.coli septicemia in calves.

Pigs: For the treatment of bacterial infections of the lungs and respiratory tract caused by Pasteurella multocida, Haemophilus parasuis, Actinobacillus pleuropneumonia, Streptococcus suis and other cefquinome-sensitive organisms Mastitis-Metritis-Agalactia syndrome (MMA) with involvement of E.coli, Staphylococcus spp., Streptococcus spp., and other cefquinome sensitive organisms.

Piglets: Reduction of mortality in cases of meningitis caused by Streptococcus suis. For the treatment of: Arthritis caused by Streptococcus ssp., E. coli, and other cefquinome-sensitive organisms. Epidermitis (mild or moderate lesions) caused by Staphylococcus hyicus.

Contraindications:

-Do not use in animals, which are known to be hypersensitive to B-lactam antibiotics.

-Do not administer to animals less than 1.25 kg body weight.

-Do not use in poultry (including eggs) due to the risk of the spread of antimicrobial resistance to humans.

Special warnings: None

Interaction with other medicinal products and other forms of Interaction:

It is known that a cross-sensitivity to cephalosporin exists for bacteria sensitive to the cephalosporin group. Due to undesirable pharmacodynamic interaction, do not apply cefquinome simultaneously with pharmaceuticals acting bacteriostatically. Withdrawal periods:

Cattle: Meat and offal, 5 days

Cattle: Milk, 24 hours.

Pigs: Meat and offal, 3 days

Poultry: Chicken: 5 days

Egg: 3days

Incompatibilities: None known

Shelf life: Shelf life 3 years

Shelf-life after first opening of the immediate packaging: 28 days.

Storage: Do not store above 25°C. Protect from light.

Dosage and Administration:

Cattle:

Digital dermatitis, infectious bulbar necrosis, and acute interdigital necrobacillosis (foul in the foot):1 mg cefquinome/kg bw (2 ml/50 kg bw), once daily for 3 or 5 consecutive days.

-Respiratory disease caused by Pasteurella multocida and M. haemolytica: 1 mg cefquinome/kg bw (2 ml/50 kg bw), once daily for 3 or 5 consecutive days.

–Acute E. coli mastitis with signs of systemic involvement: 1 mg cefquinome/kg bw (2 ml/50 kg bw), once daily for 2 consecutive days.

Calves: E. coli septicaemia: 2 mg cefquinome/kg bw (4 ml/50 kg (bw), once daily for 3 or 5 consecutive days.

Pigs: –Respiratory disease: 2 mg cefquinome/kg bw (2 ml/25 kg bw), once daily for 3 consecutive days. –MMA: 2 mg cefquinome/kg bw (2 ml/25 kg bw), once daily for 2 consecutive days.

Piglets: –Meningitis: 2 mg cefquinome/kg bw (2 ml/25 kg bw), once daily for 5 consecutive days. –Arthritis: 2 mg cefquinome/kg bw (2 ml/25 kg bw), Once daily for 5 consecutive days. –Epidermitis: 2 mg cefquinome/kg bw (2 ml/25 kg bw), Once daily for 5 consecutive days. Overdose (symptoms, emergency procedures, antidotes), if necessary overdoses of 20 mg/kg/day in cattle and 10 mg/kg/day in pigs and piglets have been well tolerated,

Poultry: Treatment against Salmonellosis, Calibacilosis CRD, and Fowl typhoid

Administration: 0.95ml/kbw-max 0.1ml/bird

N.B

All treatments to be given by intramuscular injection. Studies have indicated the advisability of giving second and subsequent injections at a different injection site. The preferred injection site is in muscular tissue in the mid-neck. To ensure a correct dosage, body weight should be determined as accurately as possible to avoid under-dosing,

Shake the vial well before using.