Amprolium is an antibiotic formula applied in drinking water of poultry, calves, lambs, young goats, cattle, and sheep and it is used as a preventive or therapeutic agent against Eimeria infections in poultry, especially E. tenella, E. necatrix, E. acervulina, and E. praecox. It is effective against other protozoal infections like Histomoniasis (Blackhead) in turkeys and poultry; against coccidiosis in calves, sheep, and goats; against amebiasis in various species.